KENNEDY SPACE CENTER, FLA. - The STS-121 crew strides out of the Operations and Checkout Building after suiting up for launch today on Space Shuttle Discovery. On the left column from back to front are Mission Specialists Thomas Reiter, Stephanie Wilson and Lisa Nowak, and Pilot Mark Kelly. On the right column from back to front are Mission Specialists Piers Sellers and Michael Fossum, with Commander Steven Lindsey leading the way. The launch is the 115th shuttle flight and the 18th U.S. flight to the International Space Station. During the 12-day mission, the STS-121 crew will test new equipment and procedures to improve shuttle safety, as well as deliver supplies and make repairs to the International Space Station. Photo courtesy of Nikon/Scott Andrews KSC-06pd1330

The Space Shuttle program was the United States government's manned launch vehicle program from 1981 to 2011, administered by NASA and officially beginning in 1972. The Space Shuttle system—composed of an orbiter launched with two reusable solid rocket boosters and a disposable external fuel tank— carried up to eight astronauts and up to 50,000 lb (23,000 kg) of payload into low Earth orbit (LEO). When its mission was complete, the orbiter would re-enter the Earth's atmosphere and lands as a glider. Although the concept had been explored since the late 1960s, the program formally commenced in 1972 and was the focus of NASA's manned operations after the final Apollo and Skylab flights in the mid-1970s. It started with the launch of the first shuttle Columbia on April 12, 1981, on STS-1. and finished with its last mission, STS-135 flown by Atlantis, in July 2011.